Mobile Mate with SanDisk Extreme not recognized on one PC but recognized on another

MobileMate with 128 gb San Disk Extreme micro SD card not recognized on one Windows 10 Pc. but is recognized on another. If I use a USB Hub, the MobileMate with SD card is recognized on first PC. Any suggestions what the problem could be?

This sounds more like a USB power, port, or driver compatibility issue on the first Windows 10 PC than a problem with the SanDisk card. Since the MobileMate works through a USB hub, try another USB port, update/reinstall the USB and card-reader drivers, and disable USB power-saving in Device Manager.