I’ve been having the same problem as many people with my My Book suddenly not being detected well here is a solution I found on the net, it may work for you.
I have the Etron USB 3 on a Gigabyte Z68 board.
Originally I just had the drive going to sleep problem and kept having to unplug and replug it back in to make it work and then all of a sudden I could not get it to be recognized anymore. I tried BIOS updates, uninstalling reinstalling the drivers but all to no avail. Strangely the drive would work in a USB2 port. After much searching I turned off HPET in the BIOS Power Management Support and immediately the drive worked again in a USB 3 port and it flies. Several reboots later it’s still working.
Hope this works for you.