Expresscache STILL won't work! (Windows 8) - SOLVED

to change IE security settings go to tools > options > security tab >reset all

That said another user had a very similar issue and found it was caused by an issue with active x. here is a link to what worked for him. can you try and see if it works for you?

http://forums.sandisk.com/t5/SanDisk-ReadyCache-SSD/Abnormal-error-running-ExpressCache/m-p/291763/highlight/true#M286