The Fuze (or any mp3 player for that matter) will work with any speaker set-up or ‘dock’ as long as they have a 3.5 mm (1/8") plug that will go into the headphone jack on the player. But do not plug an iPod-designed device into the bottom port of a Sansa player. They look very similar and will go in with a little extra effort, but are wired differently so will fry your Sansa.
Computer speakers (preferably the AC-powered ones) work great. You can usually get a decent set for around $30 US. $50 and up if you want a set with a sub-woofer.
