I have owned, and used for a long time, E260v1 and a Fuzev1, and I bought a Clip+ because of the good reviews.
I sent the Clip+ back. It simply does not sound as good as the Fuze. I really wanted to like it, but my ears kept telling me otherwise.
Frankly I don’t think it sounds any better than the E260v1, possibly worse.
It has an audible peak in the midrange–to make vocals pop out–and it has a narrower soundstage, which is to say that the music just sounds more three-dimensional and natural on the Fuze.
I carry the Fuze around in a shirt or jacket pocket all the time. I take it to the gym. It’s not fragile.
Obviously you can’t put it in a back pocket where you’d sit on it. You might–just might–be able to do that with a Clip+. I don’t think that’s worth the decrease in sound quality or battery life.