16GB Cruzer having disappearing files problem

Do you think it could be some sort of driver issue or a problem with the specific motherboard. I say this because both machines have similar motherboards. They are Asus AMD AM2+ style boards, although two different models with a couple years of time between manufacturing dates. Both machines are using the generic windows XP USB drivers and ASUS doesn’t seem to have anything newer then what windows offers for driver. Or maybe even a setting in BIOS or else where? As for heat issue, the stick isn’t getting hot at all and i don’t leave it plugged in when not in use so it would only be plugged in for 20-30mins while trying to copy the files.