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card read error

I am using a Cannon EOS XTI and I just bought a San Disk 4gb  Ultra card.  I used the card in the camera and all worked fine.  I can view pictures etc,  I took the card out and put it in my SanDisk Imagemate CF reader and now I cant see any images.  All I get is card access errors.  My Mac cant even see it at all.  I put the card back in the camera and it says I have a CF card access error and replace the card.  I did try a new card again and the same thing again.  Another dead card.  Any suggestions would be great.